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Scoring Processing System for Protein Identification in Tandem Mass Spectrometry
Valla, Martin ; Svobodová-Vařeková, Radka (referee) ; Provazník, Ivo (advisor)
The goal of my diploma thesis was finding a suitable method for unifying score values from various protein identification search tools in MS/MS mass spectrometry into one single score value. Data coming from the output of mass spectrometer are processed in two independent search tools Mascot and X!Tandem. These were selected especially for their wide usage in proteomic labs. Both results are evaluated through newly designed function and unified by single valued score clearly identifying found proteins. Newly designed scoring value is called Matascore and function producing this score was implemented in MATLAB. Function and its results were successfully tested by real data available in public databases on the Internet.
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Valuation of the Firm by Using Income Capitalization Approach
Jarošová, Lucie ; Ostrý, Petr (referee) ; Karas, Michal (advisor)
The thesis focuses on setting the financial value of company Agados Ltd. Two valuation methods, to be specific the methods DCF and EVA entity, have been used to value the company. The theoretical part deals with the issues of valuation and related areas. Subsequently, the company and the application of theoretical knowledge on Agados Ltd. are described. This work also contains strategic and financial analysis, individual steps for application of the income valuation method such as the proposal of a financial plan and capital expenses. The outcome of this thesis is the final valuation, for the needs of commercial establismet Agados Ltd., which is based on the income valuation method.
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Reversi
Labaj, Tomáš ; Jurka, Pavel (referee) ; Rozman, Jaroslav (advisor)
In this bachelor thesis present the problematic of an Artificial Intelligence and its usage for the board game Reversi is described. The best solution for this type of application is "minimax" method. To avoid redundant seeking through status field it is better to use some kind of limitations, e. c. Alpha-Beta method. Both methods are also described in this thesis. Second part is focused on self- learning computer algorithms (the ways how computer can improve his turn after unsuccessful one).
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Proposal of Changes for Human Resource Management in a Company
Svatý, Marek ; Palarčíková, Ivana (referee) ; Konečná, Zdeňka (advisor)
This bachelor thesis deals with the area of human resources and its influence on work in the company eBRÁNA ltd. The main goal of this thesis is proposal for changes of the current situation of the human resources management in the company. The theoretical part contains information about the state of human resources and its activities, which are important for good results of every company. The analytical part deals with analyses of the current condition of the human resources in the company, the results of a questionnaire and proposals for improvement of current conditions.
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Valuation of the Firm by Using Income Capitalization Approach
Jarošová, Lucie ; Ostrý, Petr (referee) ; Karas, Michal (advisor)
The thesis focuses on setting the financial value of company Agados Ltd. Two valuation methods, to be specific the methods DCF and EVA entity, have been used to value the company. The theoretical part deals with the issues of valuation and related areas. Subsequently, the company and the application of theoretical knowledge on Agados Ltd. are described. This work also contains strategic and financial analysis, individual steps for application of the income valuation method such as the proposal of a financial plan and capital expenses. The outcome of this thesis is the final valuation, for the needs of commercial establismet Agados Ltd., which is based on the income valuation method.
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|
|
Proposal of Changes for Human Resource Management in a Company
Svatý, Marek ; Palarčíková, Ivana (referee) ; Konečná, Zdeňka (advisor)
This bachelor thesis deals with the area of human resources and its influence on work in the company eBRÁNA ltd. The main goal of this thesis is proposal for changes of the current situation of the human resources management in the company. The theoretical part contains information about the state of human resources and its activities, which are important for good results of every company. The analytical part deals with analyses of the current condition of the human resources in the company, the results of a questionnaire and proposals for improvement of current conditions.
|
|
|
Reversi
Labaj, Tomáš ; Jurka, Pavel (referee) ; Rozman, Jaroslav (advisor)
In this bachelor thesis present the problematic of an Artificial Intelligence and its usage for the board game Reversi is described. The best solution for this type of application is "minimax" method. To avoid redundant seeking through status field it is better to use some kind of limitations, e. c. Alpha-Beta method. Both methods are also described in this thesis. Second part is focused on self- learning computer algorithms (the ways how computer can improve his turn after unsuccessful one).
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| |
|
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Scoring Processing System for Protein Identification in Tandem Mass Spectrometry
Valla, Martin ; Svobodová-Vařeková, Radka (referee) ; Provazník, Ivo (advisor)
The goal of my diploma thesis was finding a suitable method for unifying score values from various protein identification search tools in MS/MS mass spectrometry into one single score value. Data coming from the output of mass spectrometer are processed in two independent search tools Mascot and X!Tandem. These were selected especially for their wide usage in proteomic labs. Both results are evaluated through newly designed function and unified by single valued score clearly identifying found proteins. Newly designed scoring value is called Matascore and function producing this score was implemented in MATLAB. Function and its results were successfully tested by real data available in public databases on the Internet.
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